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Beijing
Long-term effective
2017-10-19 11:19
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shyongri(Mr.)


Beijing
Area C, Tangchen International Building, Free Trade Zone, Shanghai, Shanghai, China (200137)
| English name: | Acarbose |
|
CAS: |
56180-94-0 |
|
EINECS: |
260-030-7 |
|
Assay,% |
≥98.0% |
|
Appearance: |
Off-White Solid |
|
Molecular Formula: |
C25H43NO18 |
|
Molecular Weight |
645.6 |
| usage: | Used as an anti-diabetic. Acarbose is pseudo-oligosaccharide with a terminal C7-cyclitol patented in 1975 by Bayer. Acarbose is a component of the amylostatin complex produced by a species of Actinoplanes and Streptomyces. Acarbose acts as a potent inhibitor of alpha-glucosidases and saccharases. Since 1990, acarbose has been used therapeutically for the treatment of type 2 diabetes. |
| Biological Activity | Inhibitor of intestinal α -glucosidase (IC 50 = 11 nM). Antidiabetic; inhibits the hydrolysis of complex carbohydrates. |